Endocrine Abstracts

Purpose: We aimed to validate the diagnosis and estimated national incidence of acromegaly reported in the Swedish National Patient Register (NPR), based on clinically reported International Classification of Diseases (ICD-codes), in comparison with the Swedish Pituitary Register (SPR).Methods: All patients in NPR or SPR between 1991-2018 with the ICD-9 or ICD-10 diagnosis of acromegaly and age >18 years at diagnosis were included. The diagnosis was ...

Pituitary neuroendocrine tumors (PitNETs) are typically benign tumors presenting with symptoms related to hormone hypersecretion and/or intracranial mass. Current classification of PitNETs is based on the immunohistochemical expression of adenohypophysial hormones and three main pituitary-specific transcriptions factors PIT1, TPIT and SF1. PitNETs usually remain intrasellar, however, 20-40% of tumors show invasiveness into cavernous sinus and 6–8% infiltrate into the bone...